The Latest From Hancks Lab
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Tyron and Jessica's paper out in PLOS Pathogens
Oct. 2024
Tyron and Jessica discovered antiviral subprograms unlocked by metabolic reprogramming. Implications for how host responses evolve in real time and dysregulated immune responses associated with co-morbidities. Check it out. https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012673
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Virologs point to RNA metabolism as a battleground during infection
Sept. 2024
Collaboration with Kayla and Chris of the Sullivan Lab at UT Austin characterizing a RNA phosphatase hijacked by viruses to subdue antiviral responses https://www.biorxiv.org/content/10.1101/2024.08.06.606876v1
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Virolog chapter out in Poxvirus Book
Dec. 2024
Book chapter out describing aspects of our framework using virologs to discover host-virus interfaces
https://link.springer.com/protocol/10.1007/978-1-0716-4160-6_17
Older News:
August 2024
Former lab Ph.D. student Tyron Chang heads out for his postdoc at the USDA studying host-virus interactions
We wish you the best Tyron! Tyron was part of the first wave of the lab and a founding member. Thank you for all of your contributions - you are a rock star.
March 2024
Cynnie Tam joins the lab!
Cynnie is in the UTSW Immunology Graduate Program and hails from California. Great to have you on-board.
March 2024
Jessica Alvarez joins the lab!
Jessica is in the UTSW Medical Microbiology Graduate Program and from San Antonio. Welcome Jessica!
February 2024
Tyron Chang, one of the first Ph.D. students in the lab, defends his thesis
Tyron established a model system to study the impact of secondary cues on antiviral responses based on insights from virologs. Check out his paper in PLOS Pathogens
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012673
July 2024
When less is more: Collaboration with Ed and Zach of the Miao Lab on inflammasome protein evolution
Check it out https://academic.oup.com/gbe/article/16/7/evae138/7706372?login=true
Feb. 2024
FEAR no more: Discovery of the FEAR pathway - collaboration with the Don Gammon Lab
Work driven by Emily Rex in the Gammon Lab identified an interferon-independent antiviral pathway that is conserved to invertebrates counteracted by numerous viruses. Congrats Emily and Don!
check it out - https://www.nature.com/articles/s41564-024-01646-5